New vaccine aims to keep leukemia at bay after transplant

NCT ID NCT03679650

First seen Jan 31, 2026 · Last updated Apr 25, 2026 · Updated 12 times

Summary

This early-phase trial tests a custom-made cancer vaccine (DC/AML fusion) for people with acute myeloid leukemia who have already had a stem cell transplant. The vaccine is designed to train the immune system to find and attack any remaining leukemia cells. Some participants also receive a low-dose chemotherapy drug (decitabine) to boost the vaccine's effect. The study involves 28 adults and focuses on safety and immune response.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

Conditions

Explore the condition pages connected to this study.