Brain zaps for schizophrenia? tiny trial tests DBS when meds fail

NCT ID NCT07369401

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether deep brain stimulation (DBS) — a device that sends electrical pulses to specific brain areas — can help people with schizophrenia that hasn't improved with medication. Ten adults aged 18-55 will have electrodes implanted in two brain regions and receive different stimulation patterns over 24 weeks. The goal is to see if symptoms improve enough to make a real difference.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

deep brain stimulation (DBS) device

What this could lead to

If it works, this could point toward a new option for people with schizophrenia that doesn't respond to medication.

What could go wrong

This is a very small early study with only 10 people, so results may not apply widely. Brain surgery carries risks like infection or bleeding, and the benefit is uncertain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Schizophrenia, Treatment-Resistant treatment-refractory schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

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