New hope for kids with rare low blood sugar disorder: dasiglucagon shows promise in Long-Term trial

NCT ID NCT03941236

First seen Jan 21, 2026 · Last updated May 08, 2026 · Updated 16 times

Summary

This study tests the long-term safety of a drug called dasiglucagon in children with congenital hyperinsulinism, a rare condition causing dangerously low blood sugar. About 42 children who completed earlier trials will receive dasiglucagon as a continuous shot under the skin. The goal is to see if the drug is safe over time and helps reduce the need for extra sugar or surgery.

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Contacts and locations

Locations

  • Alder Hey Children's Hospital NHS Foundation Trust

    Liverpool, United Kingdom

  • Children's Hospital Colorado

    Aurora, Colorado, 80045-7106, United States

  • Cook Children's Endocrinology and Diabetes Clinic

    Fort Worth, Texas, 76104-2710, United States

  • Great Ormond Street Hospital for Children NHS Foundation Trust

    London, United Kingdom

  • Hadassah Medical Center

    Jerusalem, 9765422, Israel

  • Manchester University NHS Foundation Trust

    Manchester, United Kingdom

  • NHS Greater Glasgow and Clyde

    Glasgow, United Kingdom

  • Otto von Guericke University Magdeburg, Department of Pediatrics

    Magdeburg, 39120, Germany

  • The Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • University Hospital Düsseldorf, Department of Pediatrics

    Düsseldorf, 40225, Germany

Conditions

Explore the condition pages connected to this study.