New hope for aggressive lung cancer: experimental drug combo enters human testing

NCT ID NCT06077500

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 23 times

Summary

This early-phase study tests a new experimental drug called BI 764532 (obrixtamig) combined with standard chemotherapy and immunotherapy for adults with extensive-stage small cell lung cancer. The main goal is to find the highest safe dose of BI 764532 when given with standard treatments. Participants receive all treatments as infusions and are closely monitored for side effects and response.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AZ Groeninge

    Kortrijk, 8500, Belgium

  • Cliniques Universitaires Saint-Luc

    Brussels, 1200, Belgium

  • Emory University

    Atlanta, Georgia, 30322, United States

  • Fundación Jiménez Díaz

    Madrid, 28040, Spain

  • HOP Civil

    Strasbourg, 67091, France

  • Hamamatsu University Hospital

    Shizuoka, Hamamatsu, 431-3192, Japan

  • Hospital Universitario Ramon Y Cajal

    Madrid, 28034, Spain

  • Hospital Universitario Virgen De La Macarena

    Seville, 41009, Spain

  • Hôpital Louis Pradel

    Bron, 69677, France

  • INS Bergonie

    Bordeaux, 33000, France

  • Institut Gustave Roussy

    Villejuif, 94805, France

  • Instituto Valenciano de Oncología

    Valencia, 46009, Spain

  • Japanese Foundation for Cancer Research

    Tokyo, Koto-ku, 135-8550, Japan

  • MED POLONIA SP Z O O, Clinical Trials Department,Poznan

    Poznan, 60-693, Poland

  • Medical University Gdansk

    Gdansk, 80-214, Poland

  • National Cancer Center Hospital

    Tokyo, Chuo-ku, 104-0045, Japan

  • Orlando Health Cancer Institute

    Orlando, Florida, 32806, United States

  • Polish Mother's Memorial Hospital - Research Institute

    Lodz, 93-338, Poland

  • Saitama Medical University International Medical Center

    Saitama, Hidaka, 350-1298, Japan

  • University Hospital of Lausanne

    Lausanne, 1011, Switzerland

  • Universitätsklinikum Gießen und Marburg GmbH

    Giessen, 35392, Germany

Conditions

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