Promising combo targets hard-to-treat lymphoma in early trial

NCT ID NCT04915248

First seen Jan 04, 2026 · Last updated May 01, 2026 · Updated 20 times

Summary

This study tests whether adding daratumumab to standard drugs (bortezomib and dexamethasone) can shrink tumors in people with plasmablastic lymphoma, a rare and aggressive blood cancer, that has returned or not responded to prior therapy. About 28 adults will receive the combination and be monitored for response and side effects. The goal is to see if this approach can control the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • A.O. S. Maria di Terni - S.C. Oncoematologia

    NOT_YET_RECRUITING

    Terni, Italy

    Contact Email: •••••@•••••

    Contact

    Contact

  • A.O. Spedali Civili di Brescia - Ematologia

    RECRUITING

    Brescia, Italy

    Contact Email: •••••@•••••

    Contact

  • A.O. Universitaria Citta' Della Salute E Della Scienza Di Torino

    RECRUITING

    Torino, 10126, Italy

    Contact Email: •••••@•••••

    Contact

  • A.O. Universitaria Ospedali Riuniti - Ospedale Umberto I Di Ancona

    RECRUITING

    Ancona, 60126, Italy

    Contact Email: •••••@•••••

    Contact

  • A.O. Universitaria Policlinico Giaccone Di Palermo

    NOT_YET_RECRUITING

    Palermo, 90127, Italy

    Contact Email: •••••@•••••

    Contact

  • AO Arcispedale S.Maria Nuova Ematologia

    RECRUITING

    Reggio Emilia, Italy

    Contact Email: •••••@•••••

    Contact

  • AOU Integrata di Verona - U.O. Ematologia

    RECRUITING

    Verona, 37134, Italy

    Contact Email: •••••@•••••

    Contact

  • Aviano - IRCCS Centro di Riferimento Oncologico di Aviano - Divisione di Oncologia e dei Tumori immuto-correlati

    RECRUITING

    Aviano, Italy

    Contact Email: •••••@•••••

    Contact

  • Azienda Ospedaliera Universitaria Careggi - Unità funzionale di Ematologia

    RECRUITING

    Florence, 50141, Italy

    Contact Email: •••••@•••••

    Contact

  • Ematologia IRCCS Policlinico S. Matteo di Pavia

    RECRUITING

    Pavia, Italy

    Contact Email: •••••@•••••

    Contact

  • Istituto Scientifico San Raffaele, Unità Linfomi - Dipartimento Oncoematologia

    RECRUITING

    Milan, Italy

    Contact Email: •••••@•••••

    Contact

  • Milano - ASST Grande Ospedale Metropolitano Niguarda - SC Ematologia

    RECRUITING

    Miano, Italy

    Contact Email: •••••@•••••

    Contact

  • Monza - ASST MONZA Ospedale S. Gerardo - Ematologia

    RECRUITING

    Monza, Italy

    Contact Email: •••••@•••••

    Contact

  • Napoli - AORN - Azienda Ospedaliera dei Colli Monald - U.O.C. Oncologia

    ACTIVE_NOT_RECRUITING

    Naples, Italy

  • Roma - IRCCS Spallanzani - Servizio di Ematologia in malattie infettive

    NOT_YET_RECRUITING

    Roma, Italy

    Contact

    Contact

  • Roma - Ospedale S. Camillo - Ematologia

    RECRUITING

    Roma, Italy

    Contact Email: •••••@•••••

    Contact

  • Struttura Complessa di Ematologia PO TREVISO

    RECRUITING

    Treviso, 31100, Italy

    Contact Email: •••••@•••••

    Contact

  • U.O. Ematologia AO di Padova

    RECRUITING

    Padova, 35128, Italy

    Contact Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.