New drug cocktail shows promise for rare protein disease

NCT ID NCT03283917

First seen Mar 04, 2026 · Last updated Apr 25, 2026 · Updated 8 times

Summary

This early-stage trial tested the safety and best dose of three drugs—daratumumab, ixazomib, and dexamethasone—in 21 people with AL amyloidosis, a rare disease where abnormal proteins build up in organs. The goal was to find the safest combination to stop the growth of harmful cells. Participants had newly diagnosed or returning disease. The study is no longer recruiting, and results will help guide future treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for RECURRENT PRIMARY AMYLOIDOSIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.