New drug cocktail shows promise for rare protein disease

NCT ID NCT03283917

First seen Mar 04, 2026 · Last updated Jun 12, 2026 · Updated 17 times

Summary

This early-stage study tests the safety and best dose of a three-drug combination (daratumumab, ixazomib, and dexamethasone) for people with AL amyloidosis, a rare disease where abnormal proteins build up in organs. The trial includes 21 participants with newly diagnosed or returning disease. The goal is to find the safest dose and see how well the drugs control the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.