Can a diabetes drug beat metformin for antipsychotic weight gain?
NCT ID NCT07342764
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares dapagliflozin and metformin for managing weight gain caused by antipsychotic medications. About 110 adults aged 16 and older will take one of the drugs plus lifestyle advice for 26 weeks. The goal is to see which drug works better and is safer for weight control.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Dapagliflozin and metformin
- What this could lead to
- If it works, this could offer a new option to help people taking antipsychotics manage weight gain, improving their overall health.
- What could go wrong
- This is a small pilot study, so results may not apply to everyone. Side effects like dehydration or stomach issues are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
SQU
Muscat, Oman
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