Can an herbal tablet shrink gallbladder polyps without surgery?
NCT ID NCT05668871
First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time
Summary
This trial tests whether Danning tablets, an herbal medicine, can reduce the size or clear multiple gallbladder polyps when combined with lifestyle changes like a low-fat diet and avoiding alcohol. Adults aged 18-75 with polyps between 3-7 mm are enrolled. The main goal is to see if the treatment improves symptoms and shrinks polyps after 24 weeks, compared to lifestyle changes alone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Danning Tablet (Biliflow), an herbal medicine taken orally, combined with lifestyle management (diet and habits)
- What this could lead to
- If effective, Danning tablets could offer a non-surgical way to shrink or clear gallbladder polyps, potentially reducing the need for surgery.
- What could go wrong
- This is a phase 4 trial, but results are not yet known. The effect may be modest, and some people may not respond. Side effects are possible, though the medicine is already in use.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Affiliated Hospital of Shaoxing University
Shaoxing, Zhejiang, 0086575, China
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Anning First People's Hospital
Anning, Yunan, 0086871, China
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Central Hospital Affiliated to Shandong First Medical University (Jinan Central Hospital)
Jinan, Shandong, 0086531, China
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Chongqing General Hospital
Chongqing, China
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Eastern Hepatobiliary Surgery Hospital, Naval Medical University,
Shanghai, Shanghai Municipality, 0086021, China
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Ezhou Central Hospital
Ezhou, Hubei, China
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Hebei general hospital
Shijiazhuang, Hebei, China
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Jinhua Municipal Central Hospital
Jinhua, Zhejiang, 0086579, China
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Loudi Central Hospital
Loudi, Hunan, 0086738, China
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Ningbo Municipal Hospital of Traditional Chinese Medicine
Ningbo, Zhejiang, 0086574, China
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People's Hospital of Yiyang
Yiyang, Hunan, 0086737, China
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Shangrao People's Hospital
Shangrao, Jiangxi, 0086793, China
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Shanxi Traditional Chinese Medicine Hospital
Taiyuan, Shanxi, China
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Tangshan Central Hospital
Tangshan, Hebei, China
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The First Affiliated Hospital of University of South China
Hengyang, Hunan, 0086734, China
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The Sixth People's Hospital of Chengdu
Chengdu, Sichuan, 0086028, China
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Xiangya Changde Hospital
Changde, Hunan, 0086736, China
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Xiantao First People's Hospital
Xiantao, Hubei, China
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Yiwu Central Hospital
Yiwu, Zhejiang, China