New hope for rare cancers: drug duo targets BRAF mutation
NCT ID NCT05868629
First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 29 times
Summary
This study tests a combination of two targeted drugs, dabrafenib and trametinib, in people with rare solid tumors that have a specific genetic change (BRAF V600E) and cannot be removed by surgery or have spread. About 40 children and adults will receive the drugs to see how well they shrink tumors and control the disease. The goal is to improve outcomes for these hard-to-treat cancers.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for RARE UNRESECTABLE OR METASTATIC BRAF V600E MUTATION-POSITIVE SOLID TUMORS are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Locations
-
Duke Clinical Research Institute
RECRUITINGDurham, North Carolina, 27704, United States
Contact
Contact Email: •••••@•••••
-
El Paso Texas Oncology
RECRUITINGEl Paso, Texas, 79902, United States
Contact
Contact Email: •••••@•••••
-
Johns Hopkins University
RECRUITINGWashington D.C., District of Columbia, 20016, United States
Contact Email: •••••@•••••
Contact
-
Lundquist Inst BioMed at Harbor
RECRUITINGTorrance, California, 90509-2910, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Oncology Hematology Care Inc
RECRUITINGCincinnati, Ohio, 45242, United States
Contact Email: •••••@•••••
Contact
-
Rocky Mountain Cancer Centers
RECRUITINGDenver, Colorado, 80218, United States
Contact
Contact Email: •••••@•••••
-
Sarah Cannon Research Institute
RECRUITINGNashville, Tennessee, 37203, United States
Contact Email: •••••@•••••
Contact
-
Texas Oncology San Antonio
RECRUITINGSan Antonio, Texas, 78258, United States
Contact
Contact Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.