New hope for rare cancers: drug combo targets BRAF mutation
NCT ID NCT05868629
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a combination of two targeted drugs, dabrafenib and trametinib, in people with rare solid tumors that have a specific genetic change called BRAF V600E. The goal is to see how well the drugs shrink or control the tumors. The study includes both children (age 1 and older) and adults whose tumors cannot be removed by surgery or have spread to other parts of the body.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Locations
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Duke Clinical Research Institute
RECRUITINGDurham, North Carolina, 27704, United States
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Contact Email: •••••@•••••
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El Paso Texas Oncology
RECRUITINGEl Paso, Texas, 79902, United States
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Contact Email: •••••@•••••
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Johns Hopkins University
RECRUITINGWashington D.C., District of Columbia, 20016, United States
Contact Email: •••••@•••••
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Lundquist Inst BioMed at Harbor
RECRUITINGTorrance, California, 90509-2910, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Oncology Hematology Care Inc
RECRUITINGCincinnati, Ohio, 45242, United States
Contact Email: •••••@•••••
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Rocky Mountain Cancer Centers
RECRUITINGDenver, Colorado, 80218, United States
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Contact Email: •••••@•••••
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Sarah Cannon Research Institute
RECRUITINGNashville, Tennessee, 37203, United States
Contact Email: •••••@•••••
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Texas Oncology San Antonio
RECRUITINGSan Antonio, Texas, 78258, United States
Contact
Contact Email: •••••@•••••