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New pill aims to wipe out rare urinary tract cancer without surgery

NCT ID NCT07265947

Recruiting now Disease control Sponsor: Tyra Biosciences, Inc Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 04, 2026 · Updated 12 times

Summary

This study tests a new drug called dabogratinib in 230 adults with a rare, low-grade cancer in the upper part of the urinary tract. The goal is to see if the drug can make the cancer disappear completely within 6 months. Participants take the drug by mouth and are monitored for safety and response.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

renal pelvis/ureter urothelial carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LOW GRADE UPPER TRACT UROTHELIAL CARCINOMA

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Albany Medical College

    RECRUITING

    Albany, New York, 12208-3412, United States

  • Associated Medical Professionals of NY, PLLC

    RECRUITING

    Syracuse, New York, 13210, United States

  • Central Ohio Urology Group

    RECRUITING

    Gahanna, Ohio, 43230, United States

  • Cleveland Clinic

    RECRUITING

    Cleveland, Ohio, 44111, United States

  • Duly Health and Care Chicago

    RECRUITING

    Lisle, Illinois, 60532, United States

  • First Urology

    RECRUITING

    Jeffersonville, Indiana, 47130, United States

  • Greater Boston Urology - Plymouth Care Center

    RECRUITING

    Plymouth, Massachusetts, 02360, United States

  • Hospital Universitario Puerta del Mar

    RECRUITING

    Cadiz, 11009, Spain

  • Moffitt Cancer Center

    RECRUITING

    Tampa, Florida, 33612-9416, United States

  • Penn Medicine Radnor

    RECRUITING

    Radnor, Pennsylvania, 19087, United States

  • Summit Health - Washington Township

    RECRUITING

    Sewell, New Jersey, 08080-2359, United States

  • The University of Texas MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

  • The Winship Cancer Institute of Emory University

    RECRUITING

    Atlanta, Georgia, 30322-1013, United States

  • Urology Associates, P C

    RECRUITING

    Nashville, Tennessee, 37209-4035, United States

  • Urology Austin - Apex Cancer Care - Austin

    RECRUITING

    Austin, Texas, 78705-2009, United States

  • Urology of Indiana, LLC

    RECRUITING

    Greenwood, Indiana, 46143, United States

  • Urology of St. Louis

    RECRUITING

    St Louis, Missouri, 63141, United States

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