New pill could shrink rare bladder tumors without surgery

NCT ID NCT07265947

Recruiting now Disease control Sponsor: Tyra Biosciences, Inc Source: ClinicalTrials.gov ↗

First seen Jan 11, 2026 · Last updated May 16, 2026 · Updated 21 times

Summary

This study tests a new drug called dabogratinib (TYRA-300) in 230 adults with a rare, low-grade cancer in the upper urinary tract. The goal is to see if the drug can make tumors disappear completely within 6 months. Participants take the drug by mouth and are monitored for safety and response.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Cleveland Clinic
RECRUITING

Cleveland, Ohio, 44111, United States
Duly Health and Care Chicago
RECRUITING

Lisle, Illinois, 60532, United States
First Urology
RECRUITING

Jeffersonville, Indiana, 47130, United States
The University of Texas MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
Urology Associates, P C
RECRUITING

Nashville, Tennessee, 37209-4035, United States

Conditions

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LOW GRADE UPPER TRACT UROTHELIAL CARCINOMA LOW-GRADE UPPER TRACT UROTHELIAL CARCINOMA