New hope for young kids with cystic fibrosis as major drug trial begins

NCT ID NCT05422222

Recruiting now Disease control Sponsor: Vertex Pharmaceuticals Incorporated Source: ClinicalTrials.gov ↗

Summary

This study is testing a new three-drug combination therapy for children aged 1 to 11 years old who have cystic fibrosis. The main goals are to see how the drugs move through the children's bodies, check if the treatment is safe, and look for early signs that it might help control their disease. The trial will enroll about 210 children who have a specific genetic mutation that is expected to respond to this type of therapy.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

American Family Childrens Hospital
COMPLETED

Madison, Wisconsin, 53792, United States
Ann & Robert H. Lurie Children's Hospital of Chicago
COMPLETED

Chicago, Illinois, 60611, United States
Boston Children's Hospital
NOT_YET_RECRUITING

Boston, Massachusetts, 02115, United States
British Columbia Children's Hospital
NOT_YET_RECRUITING

Vancouver, Canada
CHU Lyon - Hopital Femme Mere-Enfant
NOT_YET_RECRUITING

Bron, France
Charité - Paediatric Pulmonology Department
NOT_YET_RECRUITING

Berlin, Germany
Children and Young Adults Research Unit
NOT_YET_RECRUITING

Cardiff, United Kingdom
Children's Hospital of Colorado
NOT_YET_RECRUITING

Aurora, Colorado, 80045, United States
Children's Hospital of Orange County
COMPLETED

Orange, California, 92868, United States
Children's Respiratory and Critical Care Specialists, P.A., Children's Hospitals and Clinics of Minnesota
COMPLETED

Minneapolis, Minnesota, 55404, United States
Cincinnati Children's Hospital Medical Center
COMPLETED

Cincinnati, Ohio, 45229, United States
Cohen Children's Medical Center
COMPLETED

Lake Success, New York, 11042, United States
Erasmus Medical Center / Sophia Children's Hospital
NOT_YET_RECRUITING

Rotterdam, Netherlands
Great Ormond Street Hospital for Children
NOT_YET_RECRUITING

London, United Kingdom
Hopital Necker, Enfants Malades
NOT_YET_RECRUITING

Paris, France
Inselspital - Universitaetsspital Bern
RECRUITING

Bern, Switzerland
Karolinska University Hospital - Pulmonology
NOT_YET_RECRUITING

Stockholm, Sweden
Kinderspital Zurich
NOT_YET_RECRUITING

Zurich, Switzerland
Medizinische Hochschule Hannover
NOT_YET_RECRUITING

Hanover, Germany
Nationwide Children's Hospital
COMPLETED

Columbus, Ohio, 43205, United States
Oregon Health & Science University
COMPLETED

Portland, Oregon, 97239, United States
Queensland Children's Hospital
NOT_YET_RECRUITING

South Brisbane, Australia
Rainbow Babies and Children's Hospital/University Hospitals Cleveland Medical Center
COMPLETED

Cleveland, Ohio, 44106, United States
Riley Hospital for Children at Indiana University Health
NOT_YET_RECRUITING

Indianapolis, Indiana, 46202, United States
Sahlgrenska Universitetssjukhuset
COMPLETED

Gothenburg, Sweden
Stanford University Clinical and Translational Research Unit
COMPLETED

Palo Alto, California, 94304, United States
Starship Children's Hospital
COMPLETED

Grafton, New Zealand
Texas Children's Hospital - Wallace Tower
COMPLETED

Houston, Texas, 77030, United States
The Children's Mercy Hospital
COMPLETED

Kansas City, Missouri, 64108, United States
The Emory Clinic / Children's Healthcare of Atlanta at Egleston
COMPLETED

Atlanta, Georgia, 30322, United States
The Hospital for Sick Children
NOT_YET_RECRUITING

Toronto, Canada
The Kids Research Institute Australia
NOT_YET_RECRUITING

Nedlands, Australia
The Royal Children's Hospital
NOT_YET_RECRUITING

Parkville, Australia
UPMC Children's Hospital of Pittsburgh
COMPLETED

Pittsburgh, Pennsylvania, 15224, United States
Universitatsklinikum Essen
NOT_YET_RECRUITING

Essen, Germany
Vermont Lung Center
COMPLETED

Colchester, Vermont, 05446, United States
Washington University School of Medicine / St. Louis Children's Hospital
COMPLETED

St Louis, Missouri, 63110, United States
Women's and Children's Hospital
NOT_YET_RECRUITING

North Adelaide, Australia

Conditions

Explore the condition pages connected to this study.

CYSTIC FIBROSIS