New study tracks CF patients on modern drugs to uncover hidden disease patterns

This study followed 58 adults with cystic fibrosis (CF) who were starting or switching to a new CFTR modulator medication as part of their regular care. Researchers collected blood, sputum, urine, and quality-of-life surveys before and after treatment to see how inflammation, lung bacteria, and lung function changed over time. The goal was to better understand the disease's natural history in the era of modern therapies, not to test a new drug.