BREATH OF HOPE: inhaled gene therapy tested for cystic fibrosis

NCT ID NCT03375047

Summary

This early-stage study tested a new inhaled gene therapy called MRT5005 in 42 adults with cystic fibrosis. The main goal was to check if the treatment was safe and tolerable when breathed in through a nebulizer. Researchers also looked for early signs that it might improve lung function in people with specific genetic types of cystic fibrosis.

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Contacts and locations

Locations

  • Johns Hopkins University

    Baltimore, Maryland, 21287, United States

  • Maine Medical Center

    Portland, Maine, 04102, United States

  • National Jewish Health

    Denver, Colorado, 80206, United States

  • Nationwide Children's Hospital

    Columbus, Ohio, 43205, United States

  • New Orleans Center for Clinical Research

    Knoxville, Tennessee, 37920, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Oregon Health and Sciences University

    Portland, Oregon, 97239, United States

  • University Hospitals

    Cleveland, Ohio, 44106, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35233, United States

  • University of Cincinnati

    Cincinnati, Ohio, 45267, United States

  • University of Florida

    Gainesville, Florida, 32610, United States

  • University of Indiana

    Indianapolis, Indiana, 46202, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Utah

    Salt Lake City, Utah, 84132, United States

  • Virginia Commonwealth University

    Richmond, Virginia, 23298, United States

Conditions

Explore the condition pages connected to this study.