Experimental pill tested to fight lung infections in cystic fibrosis

NCT ID NCT02649751

Summary

This study tested whether an experimental oral drug called roscovitine is safe for adults with cystic fibrosis who have a common genetic mutation and a chronic lung infection. Researchers gave different doses to 24 participants over 28 days, while 12 others received a placebo, to check for side effects and see if it reduced bacteria or inflammation. The trial was terminated early, and its main goal was to gather preliminary safety data to inform future research.

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Contacts and locations

Locations

  • CH Lyon Sud

    Lyon, 69495, France

  • CHR - Hôpital Calmette

    Lille, 59037, France

  • CHU Nantes

    Nantes, 44093, France

  • CHU de Bordeaux - Hôpital Haut-Lévêque

    Pessac, France, 33604, France

  • CHU de Nice - Hôpital Pasteur

    Nice, France, 06001, France

  • Centre Hospitalier Bretagne Atlantique

    Vannes, France, 56017, France

  • Centre de Perharidy

    Roscoff, 29684, France

  • Centre de Ressources et de Compétences de la mucoviscidose

    Reims, France, 51100, France

  • Hôpital Arnaud de Villeneuve

    Montpellier, 34295, France

  • Hôpital Cochin

    Paris, 75014, France

  • Hôpital Larrey

    Toulouse, 30030, France

Conditions

Explore the condition pages connected to this study.