New weapon tested to help antibiotics fight stubborn cystic fibrosis infections
NCT ID NCT06159725
Summary
This early-stage study tested a new drug, CMTX-101, designed to help standard inhaled antibiotics work better in adults with cystic fibrosis who have a chronic lung infection called Pseudomonas aeruginosa. The main goal was to check if a single dose given through an IV was safe and to see how the body processes the drug. Researchers also looked for early signs that the drug might help reduce the amount of bacteria in the lungs.
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Contacts and locations
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Locations
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Boston Children's Hospital
Boston, Massachusetts, 02115, United States
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Central Florida Pulmonary Group, PA
Orlando, Florida, 32803, United States
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Cystic Fibrosis Institute
Northfield, Illinois, 60093, United States
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Johns Hopkins University
Baltimore, Maryland, 21287, United States
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Lenox Hill Hospital
New York, New York, 10075, United States
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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National Jewish Health
Denver, Colorado, 80206, United States
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Nationwide Children's Hospital
Columbus, Ohio, 43205, United States
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New York Medical College
Hawthorne, New York, 10532, United States
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PennState Health
Hershey, Pennsylvania, 17003, United States
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Rainbow Babies and Children's Hospital/University Hospitals Cleveland Medical Center
Cleveland, Ohio, 44106, United States
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Seattle Children's Hospital
Seattle, Washington, 98105, United States
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St Luke's Sleep Medicine and Research Center
Boise, Idaho, 83702, United States
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Stanford University
Palo Alto, California, 94304, United States
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UPMC Children's Hospital of Pittsburgh
Pittsburgh, Pennsylvania, 15224, United States
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University of Alabama, Birmingham
Birmingham, Alabama, 35294, United States
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University of California, San Francisco
San Franciso, California, 94143, United States
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University of Kansas
Kansas City, Kansas, 66160, United States
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University of Michigan
Ann Arbor, Michigan, 48109, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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University of Utah
Salt Lake City, Utah, 84132, United States
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Vanderbilt University
Nashville, Tennessee, 37235, United States
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Virginia Commonwealth University
Richmond, Virginia, 23219, United States
Conditions
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