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Precision radiation may tame nerve tumors without surgery

NCT ID NCT07801560

Disease control Sponsor: Hartmann Oncology Radiotherapy Group, France Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 03, 2026 · Last updated Sep 09, 2026 · Updated 2 times

Summary

Researchers are reviewing records from 200 adults who received CyberKnife stereotactic radiosurgery for vestibular schwannomas, benign tumors on the nerve that controls hearing and balance. The study compares MRI scans before and after treatment to see if the tumors shrink or stop growing. It also tracks side effects, survival at six months, and quality of life using standard questionnaires. The goal is to better understand how well this precise radiation approach works as an alternative to surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
CyberKnife stereotactic radiosurgery
What this could lead to
If successful, this could confirm CyberKnife as a reliable, less invasive option for controlling vestibular schwannomas while preserving neurological function.
What could go wrong
This is a retrospective review, not a controlled trial, so it cannot prove cause and effect. Results may not apply to all patients, and side effects or incomplete data could limit conclusions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

200 people

The number who actually took part.

Started

Jan 2016

Finished

Aug 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients managed for a schwannoma at the Hartmann Radiotherapy Institute and treated with stereotactic radiotherapy .

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * ≥ 18 years old * Patients with a confirmed histopathological diagnosis of vestibular schwannoma * Patients who received stereotactic radiosurgery (SRS) for schwannoma * Patients with available data on clinical and radiological outcomes Exclusion Criteria: * Patients who received other forms of radiotherapy, surgery, or experimental treatments for the schwannoma prior to stereotactic radiotherapy * Medical records that are incomplete

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Conditions

The condition(s) this trial relates to.

acoustic neuroma Neurilemmoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Schwannoma, vestibular

Contacts and locations

Locations

  • Hartmann Oncology Radiotherapy Group

    Levallois-Perret, 92300, France