Pee test could replace scope for bladder cancer checks

NCT ID NCT05080998

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a simple urine test called CxBladder to see if it can accurately detect when bladder cancer comes back. Currently, patients need a camera inserted into the bladder (cystoscopy) for monitoring, which is uncomfortable and costly. The study will collect urine samples from 450 people with a history of bladder cancer and compare the test results to standard cystoscopy findings.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CxBladder Monitor/Monitor+ (urinary biomarker test)

What this could lead to

If successful, this urine test could replace some cystoscopies, making bladder cancer monitoring less invasive and more convenient.

What could go wrong

This is an observational study, not a treatment trial. The test may not be accurate enough to replace cystoscopy, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bladder transitional cell carcinoma Recurrence urothelial carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • James A. Haley Veteran's Hospital

    RECRUITING

    Tampa, Florida, 33612, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Miami VA Healthcare System

    RECRUITING

    Miami, Florida, 33125, United States

    Contact Email: •••••@•••••

    Contact

    Contact

  • Monash Health - Moorabbin Hospital

    RECRUITING

    Clayton, Victoria, 3165, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Ralph H. Johnson VA Health Care System

    RECRUITING

    Charleston, South Carolina, 29401, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UT Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75390, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Washington School of Medicine

    RECRUITING

    Seattle, Washington, 98195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

  • White River Junction Veterans Affair Medical Center

    RECRUITING

    White River Junction, Vermont, 05009, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••