New Two-Drug attack targets Hard-to-Treat advanced cancers

NCT ID NCT07446049

First seen Mar 05, 2026 · Last updated Apr 09, 2026 · Updated 5 times

Summary

This study is testing a new combination of an oral tablet (CVL237) and an immunotherapy injection (serplulimab) for people with advanced solid tumors that have a specific genetic feature called PTEN loss or low expression. The main goals are to find the safest and most effective dose and to see how well the combination controls cancer growth and extends the time before the disease gets worse. It is for adults with certain advanced cancers who have already tried standard treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for LOCALLY ADVANCED OR METASTATIC SOLID TUMORS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

Explore the condition pages connected to this study.