New combo therapy aims to tackle Hard-to-Treat cancers
NCT ID NCT07157956
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests a new drug called CVL006 combined with standard chemotherapy or other targeted drugs in people with advanced solid tumors that have not responded to previous treatments. The trial has two phases: first, to find the safest dose, and second, to see if the combination helps slow cancer growth. About 318 participants will be enrolled across multiple centers.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- CVL006 combined with chemotherapy (pemetrexed, carboplatin) or targeted drugs (SKB264, DS-8201, Enfortumab Vedotin)
- What this could lead to
- If successful, this could point toward new combination treatments for advanced solid tumors that have stopped responding to standard therapies.
- What could go wrong
- This is an early-phase trial (Phase I/II) with a small number of participants, so safety and efficacy are not yet established. The combinations may cause significant side effects or fail to shrink tumors.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Sun Yat-sen University Cancer Center
Guangzhou, Guangdong, 510060, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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