Major trial launches to find better treatments for Flesh-Eating parasite

NCT ID NCT07463040

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 3 trial in Ethiopia will compare four different drug regimens against the standard treatment for cutaneous leishmaniasis, a parasitic skin disease. 900 patients aged 4 to 65 will be hospitalized and treated for up to 28 days, with follow-up for 6 months. The goal is to see which treatment cures all skin lesions by day 90.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Sodium Stibogluconate, Miltefosine, Paromomycin, Liposomal Amphotericin B, Pentamidine isethionate

What this could lead to

If successful, this trial could identify a more effective treatment for cutaneous leishmaniasis, reducing the burden of this disfiguring disease in Ethiopia.

What could go wrong

This is a large Phase 3 trial, but results may not apply to other regions or parasite strains. Some treatments have side effects like kidney or liver issues.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cutaneous leishmaniasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • ALERT Hospital

    Addis Ababa, Ethiopia

    Contact

    Contact Email: •••••@•••••

  • Arba Minch General Hospital

    Arba Minch, Ethiopia

    Contact Email: •••••@•••••

    Contact

  • Boru Meda General Hospital

    Boru, Ethiopia

    Contact Email: •••••@•••••

    Contact