Tailored drug dosing aims to control blood cancer while reducing side effects

NCT ID NCT05963074

Recruiting now Disease control Sponsor: Janssen Research & Development, LLC Source: ClinicalTrials.gov ↗

Summary

This study is testing different ways to give the drug ibrutinib, either alone or with another drug called venetoclax, to people with previously untreated chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). The goal is to find dosing strategies that effectively control the cancer while proactively or reactively adjusting the dose to better manage side effects. Researchers will enroll about 320 participants to compare how well these customized treatment approaches work and how safe they are.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

ASST Grande Ospedale Metropolitano Niguarda
RECRUITING

Milan, 20162, Italy
Azienda Ospedaliera di Perugia Ospedale S.Maria della Misericordia
RECRUITING

Perugia, 06132, Italy
Azienda Ospedaliero Universitaria Careggi
RECRUITING

Florence, 50134, Italy
Azienda Ospedaliero-Universitaria di Ferrara Arcispedale Sant Anna
RECRUITING

Ferrara, 44124, Italy
Boise VA Medical Center
RECRUITING

Boise, Idaho, 83702, United States
CHU Lyon Sud
RECRUITING

Pierre-Bénite, 69495, France
CHU Nantes
RECRUITING

Nantes, 44000, France
CHU de Clermont Ferrand
COMPLETED

Clermont-Ferrand, 63100, France
CHU de Reims
RECRUITING

Reims, 51100, France
Cancer and Blood Specialty Clinic
RECRUITING

Los Alamitos, California, 90720, United States
Centrum Onkologii Ziemi Lubelskiej im sw Jana z Dukli
RECRUITING

Lublin, 20 090, Poland
Community Cancer Trials of Utah
RECRUITING

Ogden, Utah, 84405, United States
Ematologia Fondazione Univ. Policlinico Gemelli Università Cattolica del Sacro Cuore
RECRUITING

Roma, 00136, Italy
Fakultni Nemocnice Ostrava
RECRUITING

Ostrava - Poruba, 708 52, Czechia
Fakultni nemocnice Brno
RECRUITING

Brno-Bohunice, 625 00, Czechia
Fakultni nemocnice Hradec Kralove
RECRUITING

Hradec Králové, 500 05, Czechia
Fakultni nemocnice Kralovske Vinohrady
RECRUITING

Prague, 100 34, Czechia
Fakultni nemocnice Olomouc
RECRUITING

Olomouc, 779 00, Czechia
Grand Valley Oncology
RECRUITING

Grand Junction, Colorado, 81505, United States
Gyor Moson Sopron Varmegyei Petz Aladar Egyetemi Oktato Korhaz
RECRUITING

Győr, 9024, Hungary
Hematology Oncology Associates of Rockland
RECRUITING

Nyack, New York, 10960, United States
Hope and Healing Cancer Services
RECRUITING

Hinsdale, Illinois, 60521, United States
Hopital Pitie Salpetriere
RECRUITING

Paris, 75651, France
Hosp Reina Sofia
RECRUITING

Córdoba, 14004, Spain
Hosp Univ Vall D Hebron
RECRUITING

Barcelona, 08035, Spain
Hosp. Clinico Univ. de Santiago
RECRUITING

Santiago de Compostela, 15706, Spain
Hosp. Univ. 12 de Octubre
RECRUITING

Madrid, 28041, Spain
Hosp. Univ. Marques de Valdecilla
RECRUITING

Santander, 39008, Spain
Hosp. Univ. Ramon Y Cajal
RECRUITING

Madrid, 28034, Spain
Hunterdon Hematology Oncology
RECRUITING

Flemington, New Jersey, 08822, United States
Institut de Cancerologie Strasbourg Europe ICANS
COMPLETED

Strasbourg, 67200, France
Iowa City VA Health Care System
RECRUITING

Iowa City, Iowa, 52246, United States
Mid Florida Hematology Oncology
RECRUITING

Orange, Florida, 32763, United States
Minnesota Oncology Hematology P A
RECRUITING

Minneapolis, Minnesota, 55404, United States
Mount Sinai Medical Center Campus
RECRUITING

Miami Beach, Florida, 33140-2948, United States
Niagara Health System
RECRUITING

St. Catharines, Ontario, L2S 0A9, Canada
Northwest Cancer Specialists PC
RECRUITING

Vancouver, Washington, 98684, United States
OHSU Knight Cancer Institute
RECRUITING

Portland, Oregon, 97239, United States
Oncology Hematology Care
RECRUITING

Cincinnati, Ohio, 45242, United States
Ospedale Maggiore della Carita
RECRUITING

Novara, 28100, Italy
Ospedale San Raffaele
RECRUITING

Milan, 20132, Italy
Ospedale Villa Sofia-Cervello
RECRUITING

Palermo, 90146, Italy
PIH Health Hospital
RECRUITING

Whittier, California, 90602, United States
Providence Medical Foundation
RECRUITING

Santa Rosa, California, 95403, United States
QEII Health Sciences Centre
RECRUITING

Halifax, Nova Scotia, B3H 1V7, Canada
Renovatio Clinical
COMPLETED

The Woodlands, Texas, 77380, United States
Research Medical Center
RECRUITING

Kansas City, Missouri, 64132, United States
SLO Oncology and Hematology Health Center
RECRUITING

San Luis Obispo, California, 93401, United States
Samodzielny Publiczny Zaklad Opieki Zdrowotnej Szpital Uniwersytecki w Krakowie
RECRUITING

Krakow, 30 688, Poland
Semmelweis Egyetem
RECRUITING

Budapest, 1088, Hungary
Southeastern Medical Oncology Center
COMPLETED

Goldsboro, North Carolina, 27534, United States
Springfield Clinic
RECRUITING

Springfield, Illinois, 62702, United States
Summit Medical Group
COMPLETED

Florham Park, New Jersey, 07932, United States
Swietokrzyskie Centrum Onkologii SPZOZ w Kielcach
RECRUITING

Kielce, 25 734, Poland
Szabolcs Szatmar Bereg Varmegyei Oktatokorhaz
RECRUITING

Nyíregyháza, 4400, Hungary
Szpital Specjalistyczny w Brzozowie
RECRUITING

Brzozów, 36 200, Poland
Szpitale Pomorskie Sp z o o
RECRUITING

Gdynia, 81-519, Poland
Texas Oncology-Fort Worth Cancer Center
RECRUITING

Fort Worth, Texas, 76104, United States
Texas Oncology-Gulf Coast
RECRUITING

The Woodlands, Texas, 77380, United States
The Oncology Institute
RECRUITING

North Miami Beach, Florida, 33169, United States
The Oncology Institute Clinical Research
RECRUITING

Cerritos, California, 90703, United States
The University of Texas MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
U.O. Ematologia Istituto Tumori Giovanni Paolo II
RECRUITING

Bari, 70124, Italy
Umberto I Policlinico di Roma
RECRUITING

Roma, 00161, Italy
Universita degli Studi di Padova Azienda Ospedaliera di Pa
RECRUITING

Padua, 35129, Italy
University of Szeged
RECRUITING

Szeged, 6725, Hungary
Ustav Hematologie A Krevni Transfuze
RECRUITING

Prague, 128 00, Czechia
VA Puget Sound Healthcare System
RECRUITING

Seattle, Washington, 98108, United States
Virginia Cancer Specialists
RECRUITING

Manassas, Virginia, 20110, United States
Virginia Oncology Associates
RECRUITING

Virginia Beach, Virginia, 23456, United States
Willamette Valley Cancer Institute and Research Center
RECRUITING

Eugene, Oregon, 97401, United States
Wojewodzki Szpital Specjalistyczny
RECRUITING

Biała Podlaska, 21 500, Poland
Wojewodzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im M Kopernika w Lodzi
RECRUITING

Lodz, 93 513, Poland

Conditions

Explore the condition pages connected to this study.

LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL SMALL LYMPHOCYTIC LYMPHOMA