Immune cells from donors may fight deadly brain virus in new trial

NCT ID NCT06990087

Recruiting now Disease control Sponsor: Hannover Medical School Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 31 times

Summary

This study tests a new treatment made from donor immune cells that target the virus causing PML, a rare and serious brain infection. About 23 adults with PML (not caused by HIV or certain drugs) will receive these cells. The goal is to see if the treatment is safe, helps patients live longer, and improves their quality of life.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Hannover Medical School
RECRUITING

Hanover, Lower Saxony, 30625, Germany

Contact
LMU Klinikum Campus Großhadern
NOT_YET_RECRUITING

München, Bavaria, 81377, Germany

Contact
Universitätsklinikum Düsseldorf
NOT_YET_RECRUITING

Düsseldorf, North Rhine-Westphalia, 40225, Germany
Universitätsklinikum Essen
NOT_YET_RECRUITING

Essen, North Rhine-Westphalia, 45147, Germany
Universitätsklinikum Marburg
NOT_YET_RECRUITING

Marburg, Hesse, Germany
Universitätsklinikum Schleswig-Holstein
NOT_YET_RECRUITING

Kiel, Schleswig-Holstein, 24105, Germany

Conditions

Explore the condition pages connected to this study.

PROGRESSIVE MULTIFOCAL LEUCOENCEPHALOPATHY (PML)