Gene-Edited immune cells take on Hard-to-Treat blood cancers
NCT ID NCT05643742
First seen Nov 03, 2025 · Last updated Apr 24, 2026 · Updated 20 times
Summary
This study tests a new treatment called CTX112 for people with B-cell blood cancers that have come back or not responded to standard therapy. CTX112 uses CRISPR gene editing to modify donor immune cells so they can better find and attack cancer cells. The trial has two parts: first, finding the safest dose, then expanding to see how well it works in up to 120 adults.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Alfred Health
RECRUITINGMelbourne, Victoria, 3004, Australia
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Royal Prince Alfred
RECRUITINGCamperdown, New South Wales, 2050, Australia
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SCRI
RECRUITINGSan Antonio, Texas, 78229, United States
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Sir Charles Gairdner Hospital
RECRUITINGNedlands, Western Australia, 6009, Australia
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University of Kansas
RECRUITINGWestwood, Kansas, 66205, United States
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University of Utah
RECRUITINGSalt Lake City, Utah, 84112, United States
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Washington University
RECRUITINGSt Louis, Missouri, 63110, United States
Conditions
Explore the condition pages connected to this study.