CRISPR Gene-Editing takes on blood cancers in new trial

NCT ID NCT05643742

First seen Nov 03, 2025 · Last updated May 24, 2026 · Updated 25 times

Summary

This study tests a new treatment called CTX112 for people with B-cell blood cancers (like lymphoma or leukemia) that have come back or not responded to standard therapy. CTX112 uses CRISPR gene-editing to create donor T-cells that target and kill cancer cells. The trial involves about 120 adults and aims to check safety and how well the treatment shrinks tumors.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Alfred Health

    RECRUITING

    Melbourne, Victoria, 3004, Australia

  • Royal Prince Alfred

    RECRUITING

    Camperdown, New South Wales, 2050, Australia

  • SCRI

    RECRUITING

    San Antonio, Texas, 78229, United States

  • Sir Charles Gairdner Hospital

    RECRUITING

    Nedlands, Western Australia, 6009, Australia

  • University of Kansas

    RECRUITING

    Westwood, Kansas, 66205, United States

  • University of Utah

    RECRUITING

    Salt Lake City, Utah, 84112, United States

  • Washington University

    RECRUITING

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.