New drug combo targets tough brain cancers in early trial

NCT ID NCT01107522

First seen Nov 01, 2025 · Last updated May 07, 2026 · Updated 19 times

Summary

This early-phase study tests an experimental oral drug called CTO, alone or combined with standard treatments, in 100 adults with advanced solid tumors or aggressive brain cancers (glioblastoma). The main goal is to find the safest dose and understand side effects. Researchers will also check if the drug helps shrink tumors.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for SOLID TUMORS, GLIOBLASTOMA, RECURRENT MALIGNANT GLIOMAS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Memorial Sloan-Kettering Cancer Center

    New York, New York, 10017, United States

  • New York University

    New York, New York, 10016, United States

  • Oregon Health and Sciences University

    Portland, Oregon, 97239, United States

  • Providence Cancer Center

    Portland, Oregon, 97213, United States

Conditions

Explore the condition pages connected to this study.