New drug CT1812 tested for lewy body dementia

NCT ID NCT05225415

Completed Disease control Sponsor: Cognition Therapeutics Source: ClinicalTrials.gov ↗

First seen Apr 20, 2026 · Last updated May 15, 2026 · Updated 5 times

Summary

This study tested a drug called CT1812 in 130 people with mild to moderate Dementia with Lewy Bodies. The goal was to see if the drug is safe and if it can help with symptoms like thinking and sleepiness. Participants received either the drug or a placebo for 6 months, and researchers tracked side effects and changes in their condition.

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Contacts and locations

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Locations

Banner Sun Health Research Institute

Sun City, Arizona, 85351, United States
Barrow Neurological Institute

Phoenix, Arizona, 85013, United States
CenExel Rocky Mountain Clinical Research, LLC

Englewood, Colorado, 80113, United States
Charter Research

Lady Lake, Florida, 32156, United States
Charter Research

Winter Park, Florida, 32792, United States
Cleveland Clinic Main Campus

Cleveland, Ohio, 44195, United States
Clinical Trial Network

Houston, Texas, 77074, United States
Columbia University

New York, New York, 10032, United States
Evergreen Health Research

Kirkland, Washington, 98034, United States
Headlands Research Eastern Massachusetts, LLC

Plymouth, Massachusetts, 02360, United States
IU Health Neuroscience Center, Goodman Hall

Indianapolis, Indiana, 46202, United States
JEM Research Institute

Atlantis, Florida, 33462, United States
Josephson Wallack Munshower Neurology, P.C

Indianapolis, Indiana, 46256, United States
Mayo Clinic

Rochester, Minnesota, 55905, United States
New England Institute for Neurology and Headache (NEINH)

Stamford, Connecticut, 06905, United States
Ohio State University

Columbus, Ohio, 43210, United States
Oregon Health and Science University

Portland, Oregon, 97239, United States
Pacific Neuroscience Institute

Santa Monica, California, 90404, United States
Parkinson's Disease and Movement Disorders Center of Boca Raton

Boca Raton, Florida, 33486, United States
Renstar Medical Research

Ocala, Florida, 34770, United States
Rush University Medical Center Section of Parkinson Disease and Movement Disorder

Chicago, Illinois, 60612, United States
Stanford University

Palo Alto, California, 94304, United States
Summit Headlands, LLC

Portland, Oregon, 97210, United States
The University of Kansas Alzheimer's Disease Research Center

Fairway, Kansas, 66205, United States
UNC Department of Neurology

Chapel Hill, North Carolina, 27599, United States
University of Arizona - Health Sciences Center

Tucson, Arizona, 85724, United States
University of Colorado

Aurora, Colorado, 80045, United States
University of Kentucky

Lexington, Kentucky, 40504, United States
University of Miami Miller School of Medicine Comprehensive Center for Brain Health

Boca Raton, Florida, 33433, United States
University of Pennsylvania

Philadelphia, Pennsylvania, 19107, United States
University of Texas Southwestern

Dallas, Texas, 75390, United States
University of Virginia Adult Neurology

Charlottesville, Virginia, 22903, United States
Universtiy of Washington Department of Neurology

Seattle, Washington, 98104, United States
Virginia Commonwealth University

Richmond, Virginia, 23298, United States

Conditions

Explore the condition pages connected to this study.

DEMENTIA WITH LEWY BODIES