New drug aims to cut short sickle cell pain attacks

NCT ID NCT06699849

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an investigational drug called CSL889 in 70 adults and adolescents with sickle cell disease who are having a painful vaso-occlusive crisis. The goal is to see if the drug can safely shorten the crisis and reduce the need for strong pain medicines. Participants will receive either CSL889 or a placebo by IV, and researchers will monitor how quickly the pain resolves and any side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute chest syndrome acute kidney injury sickle cell disease Vaso-Occlusive Crises

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Detroit Medical Center

    RECRUITING

    Detroit, Michigan, 48201, United States

  • East Carolina University

    RECRUITING

    Greenville, North Carolina, 27834, United States

  • Golisano Children's Hospital

    RECRUITING

    Fort Myers, Florida, 33908, United States

    Contact

  • Hacettepe Universitesi

    NOT_YET_RECRUITING

    Ankara, 06230, Turkey (Türkiye)

    Contact

  • Henry Ford Health System

    RECRUITING

    Detroit, Michigan, 48202, United States

    Contact

  • Hillman Cancer Center

    RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

  • Istanbul Universitesi

    NOT_YET_RECRUITING

    Istanbul, 34093, Turkey (Türkiye)

    Contact

  • Jacobi Medical Center

    RECRUITING

    The Bronx, New York, 10461, United States

    Contact

  • Mount Sinai Medical Center

    RECRUITING

    New York, New York, 10029, United States

    Contact

  • The Foundation for Sickle Cell Disease

    RECRUITING

    Hollywood, Florida, 33023-6703, United States

    Contact

  • The Ohio State University

    RECRUITING

    Columbus, Ohio, 43085, United States

    Contact

  • Univ. of California, San Francisco Health Care

    RECRUITING

    Oakland, California, 94609, United States

  • University of California Irvine

    NOT_YET_RECRUITING

    Orange, California, 92868, United States

    Contact

  • University of Cincinnati

    RECRUITING

    Cincinnati, Ohio, 45267, United States

    Contact

  • University of Louisville Hospital

    RECRUITING

    Louisville, Kentucky, 40202, United States

  • University of Maryland

    RECRUITING

    Baltimore, Maryland, 21201, United States

    Contact

  • University of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15224, United States

  • Virginia Commonwealth University

    RECRUITING

    Richmond, Virginia, 23298, United States

  • Özel Acibadem Adana Hastanesi

    NOT_YET_RECRUITING

    Seyhan, 01130, Turkey (Türkiye)

    Contact