Chill out tooth pain: cold saline injection beats ice water after root canal
NCT ID NCT06304259
First seen Nov 19, 2025 · Last updated Apr 28, 2026 · Updated 18 times
Summary
This study tested two ways of using cold therapy (cryotherapy) to reduce pain after a root canal in people with severe toothache. Forty-five adults with an infected lower premolar were divided into three groups: one got a cold saline injection near the tooth, another had ice-cold water placed inside the tooth canal, and a third received standard care. Pain levels were measured at 12, 24, and 48 hours after treatment. The goal was to find which cold method works best for easing post-procedure discomfort.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Faculty of Dentistry, Ain shams University
Cairo, 4543070, Egypt
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