Heart rhythm showdown: freezing vs burning for AFib

NCT ID NCT01490814

First seen Apr 25, 2026 · Last updated Jun 12, 2026 · Updated 6 times

Summary

This study compared two ways to treat a common heart rhythm problem called atrial fibrillation (AFib). One method uses a freezing balloon (cryoballoon) and the other uses heat (radiofrequency) to fix the heart's electrical signals. About 769 adults with AFib took part. The goal was to see which method works better and is safer at controlling symptoms without needing more drugs or repeat procedures.

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Contacts and locations

Locations

  • Arrhythmia Unit Hospital Clinico San Carlos

    Madrid, 28040, Spain

  • Asklepios Klinik St. Georg

    Hamburg, 20099, Germany

  • CHU Lyon, Départment de Rythmologie, Hospital Cardiologique Pradel

    Lyon, 69677, France

  • Cardiac Arrhythmia Research Centre Department of Cardiovascular Medicine Centro Cardiologico Monzino University of Milan

    Milan, 20138, Italy

  • Cardioangiologisches Centrum Bethanien - CCB

    Frankfurt, 60431, Germany

  • Centre Chirurgical Ambroise Paré

    Neuilly-sur-Seine, 92200, France

  • Herz-Zentrum Bad Krozingen

    Bad Krozingen, 79189, Germany

  • Herz-Zentrum-Bodensee Konstanz

    Konstanz, 78464, Germany

  • Hospital Clinic, University of Barcelona

    Barcelona, 08036, Spain

  • Hospital Clinico Universtitario, Cardiology Department Arrhythmia Unit

    Valencia, 46014, Spain

  • Hospital Henri Mondor CHU, Service de Cardiologie

    Créteil, 94010, France

  • Hospital Universitario Virgen de la Victoria, Department of Cardiology, Campus Teatinos sn

    Málaga, 29010, Spain

  • Isala Klinieken loc. Weezenlanden Diagram Clinical Resarch

    Zwolle, 8011, Netherlands

  • Klinik für Kardiologie II mit interventioneller Elektrophysiologie

    Bad Neustadt/Saale, 97616, Germany

  • La Clinique Pasteur, 45 Avenue de Lombez

    Toulouse, 31076, France

  • Na Homolce Hospital, Cardiology

    Prague, 515030, Czechia

  • Semmelweis University of Medicine, Kardiovaskuläres Zentrum

    Budapest, 1122, Hungary

  • Universitätsklinikum Greifswald Elektrophysiologie

    Greifswald, 17475, Germany

  • Universitätsspital Basel, Elektrophysiologie/ Kardiologie

    Basel, 4031, Switzerland

Conditions

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