New combo treatment for Rock-Hard arteries shows promise in clinical trial

NCT ID NCT07279987

Not yet recruiting Disease control Sponsor: Lin Zhao Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two methods to treat severely calcified coronary arteries: one uses a special balloon that inflates at very high pressure, and the other combines a rotating burr with sound waves to break up calcium. Researchers will enroll 162 adults with hardened arteries to see which approach leads to better stent placement and fewer complications. Participants will be followed for one year to track heart health and safety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Rotational atherectomy device, intravascular lithotripsy device, and super high-pressure balloon

What this could lead to

If successful, this could offer a safer and more effective way to open heavily calcified heart arteries, improving stent placement and reducing complications.

What could go wrong

This is an early-stage trial with only 162 participants, so results may not apply to everyone. Both techniques carry risks like artery damage or blockages.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

calcinosis coronary artery disorder coronary atherosclerosis Vascular Calcification

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Chaoyang Hospital,Capital Medical University

    Beijing, Beijing Municipality, 100020, China