New drug trial aims to control rare blood disease in untreated patients

NCT ID NCT04654468

Summary

This study is testing whether the drug crovalimab can safely control paroxysmal nocturnal hemoglobinuria (PNH), a rare blood disease where the immune system destroys red blood cells. The trial includes about 50 people aged 12 and older with PNH who have never taken similar complement inhibitor medicines. Participants receive crovalimab for at least 24 weeks while researchers measure how well it controls blood cell destruction and reduces the need for blood transfusions.

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Contacts and locations

Locations

  • Institute of Hematology and Hospital of Blood Disease

    Tianjin, 300020, China

  • Tianjin Medical University General Hospital

    Tianjin, 300052, China

  • Union Hospital Tongji Medical College Huazhong University of Science and Technology

    Wuhan, 430022, China

  • West China Hospital, Sichuan University

    Chengdu, 610041, China

Conditions

Explore the condition pages connected to this study.