New hope for rare blood disorder: crovalimab trial underway
NCT ID NCT03157635
First seen Nov 17, 2025 · Last updated Apr 28, 2026 · Updated 18 times
Summary
This study tests a new medicine, crovalimab, in healthy volunteers and people with paroxysmal nocturnal hemoglobinuria (PNH), a rare blood disease that destroys red blood cells. The goal is to see if the drug is safe and can control the disease by blocking part of the immune system. About 59 participants will receive the drug, and researchers will monitor side effects and how well it works.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Institut hematologie Centre Hayem CHU paris Saint-Louis Lariboisiere F Widal Hopital St Louis
Paris, 75475, France
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Kaposi Mor Teaching Hospital, Dept of Internal Medicine/Hematology
Kaposvár, 7400, Hungary
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NTT Medical Center Tokyo
Tokyo, 141-8625, Japan
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Osaka University Hospital
Osaka, 565-0871, Japan
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Policlinico Universitario Agostino Gemelli
Rome, Lazio, 00168, Italy
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Pra International Group B.V
Groningen, 9713 GZ, Netherlands
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Semmelweis Egyetem, 1. Szamu Belgyogyaszati Klinika, Diabetologia
Budapest, 1083, Hungary
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Seoul National University Hosp
Seoul, 110-744, South Korea
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Tohoku University Hospital
Miyagi, 980-8574, Japan
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Tokyo Medical University Hospital
Tokyo, 160-0023, Japan
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Uniklinik RWTH Aachen
Aachen, 52074, Germany
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University of Tsukuba Hospital
Tsukuba, 305-8576, Japan
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Universitätsklinikum Essen
Essen, 45122, Germany
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Universitätsklinikum Ulm
Ulm, 89081, Germany
Conditions
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