New drug trial offers hope for controlling rare blood disorder

NCT ID NCT03157635

Summary

This early-stage study is testing a new drug called crovalimab for people with paroxysmal nocturnal hemoglobinuria (PNH), a rare and serious blood disease. The main goals are to check if the drug is safe, how the body processes it, and if it can help control the disease. The study involves both healthy volunteers and people with PNH, testing different doses and schedules.

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Contacts and locations

Locations

  • Institut hematologie Centre Hayem CHU paris Saint-Louis Lariboisiere F Widal Hopital St Louis

    Paris, 75475, France

  • Kaposi Mor Teaching Hospital, Dept of Internal Medicine/Hematology

    Kaposvár, 7400, Hungary

  • NTT Medical Center Tokyo

    Tokyo, 141-8625, Japan

  • Osaka University Hospital

    Osaka, 565-0871, Japan

  • Policlinico Universitario Agostino Gemelli

    Rome, Lazio, 00168, Italy

  • Pra International Group B.V

    Groningen, 9713 GZ, Netherlands

  • Semmelweis Egyetem, 1. Szamu Belgyogyaszati Klinika, Diabetologia

    Budapest, 1083, Hungary

  • Seoul National University Hosp

    Seoul, 110-744, South Korea

  • Tohoku University Hospital

    Miyagi, 980-8574, Japan

  • Tokyo Medical University Hospital

    Tokyo, 160-0023, Japan

  • Uniklinik RWTH Aachen

    Aachen, 52074, Germany

  • University of Tsukuba Hospital

    Tsukuba, 305-8576, Japan

  • Universitätsklinikum Essen

    Essen, 45122, Germany

  • Universitätsklinikum Ulm

    Ulm, 89081, Germany

Conditions

Explore the condition pages connected to this study.