New drug trial offers hope for controlling rare blood disorder

NCT ID NCT04861259

Summary

This study is testing an investigational drug called crovalimab in adults and adolescents with atypical hemolytic uremic syndrome (aHUS), a rare and serious blood disorder that can damage the kidneys. The main goal is to see if the drug can effectively control the disease and is safe for patients. It includes people new to this type of treatment and those switching from other similar medications.

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Contacts and locations

Locations

  • A.O. Universitaria S. Martino Di Genova

    Genoa, Liguria, 16132, Italy

  • All India Institute Of Medical Sciences (AIIMS)

    New Delhi, National Capital Territory of Delhi, 110029, India

  • Children's Hospital Colorado

    Aurora, Colorado, 80045, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Del- Pesti Centrumkorhaz- Szent Laszlo Korhaz Telephely

    Budapest, 1097, Hungary

  • Emory Children's Center

    Atlanta, Georgia, 20010, United States

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS

    Rome, Lazio, 00168, Italy

  • Hopital Lapeyronie

    Montpellier, 34295, France

  • Hopital Tenon

    Paris, 75970, France

  • Hospital Clinic i Provincial

    Barcelona, 08036, Spain

  • Hospital General de México

    Distrito Federal, Mexico CITY (federal District), 06726, Mexico

  • Hospital Universitario "Dr. Jose Eleuterio Gonzalez"

    Monterrey, Nuevo León, 64460, Mexico

  • Hospital Universitario Virgen del Rocío

    Seville, 41013, Spain

  • Hospital das Clinicas - FMUSP

    São Paulo, São Paulo, 05403-000, Brazil

  • Hospital de Especialidades Puerta de Hierro S.A de C.V.

    Zapopan, 45116, Mexico

  • Hôpital Arnaud de Villeneuve

    Montpellier, 34295, France

  • Hôpital Robert Debré

    Paris, 75019, France

  • Instituto Nacional de Ciencias

    Mexico City, Mexico CITY (federal District), 14080, Mexico

  • Instytut ?Centrum Zdrowia Matki Polki

    Lodz, 93-338, Poland

  • Istanbul University Istanbul Medical Faculty

    Istanbul, 34390, Turkey (Türkiye)

  • Klinik II für Nephrologie, Rheumatologie, Diabetologie und Allgemeine Innere Medizin

    Cologne, 50937, Germany

  • Klinik für Nephrologie des Universitätsklinikum Essen

    Essen, 45147, Germany

  • Kocaeli University Medical Faculty

    Kocaeli, 41380, Turkey (Türkiye)

  • Malatya Park Hospital

    Malatya, 44330, Turkey (Türkiye)

  • Medanta-The Medicity

    Gurgaon, Haryana, 122001, India

  • Medizinische Hochschule Hannover

    Hanover, 30625, Germany

  • Nagoya University Hospital

    Aichi, 466-8560, Japan

  • Necmettin Erbakan University Meram Medical Faculty

    Konya, 42080, Turkey (Türkiye)

  • Peking University First Hospital

    Beijing, 100034, China

  • Rabin Medical Center

    Petah Tikva, 49100, Israel

  • Rambam Medical Center

    Haifa, 3109601, Israel

  • Saitama Medical University Hospital

    Saitama, 350-0451, Japan

  • Santa Casa de Misericordia

    Belo Horizonte, Minas Gerais, 30150-221, Brazil

  • Sheba MC

    Ramat Gan, 52621, Israel

  • The Ohio State University Wexner Medical Center

    Columbus, Ohio, 43212, United States

  • The University of Tokyo Hospital

    Tokyo, 113-8655, Japan

  • UPECLIN Hospital das Clinicas da Faculdade de Medicina de Botucatu

    Botucatu, São Paulo, 18618-686, Brazil

  • UT Health Science Center

    San Antonio, Texas, 78229, United States

  • UZ Leuven Gasthuisberg

    Leuven, 3000, Belgium

  • Univ of CA San Francisco

    San Francisco, California, 94143, United States

  • Universitätsklinikum Essen

    Essen, 45122, Germany

  • Vancouver General Hospital

    Vancouver, British Columbia, V5Z 2S3, Canada

  • Washington University

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.