Can CrossFit reboot the immune system? blood study in sedentary men
NCT ID NCT07824830
First seen Sep 17, 2026 · Last updated Sep 18, 2026 · Updated 1 time
Summary
Researchers at Inonu University are studying how an eight-week CrossFit program affects the immune systems of sedentary male university students. Thirty participants will complete one acute CrossFit session and then train three days a week for eight weeks. Blood samples collected before and after the acute session and after the full program will show whether immune cell counts change with high-intensity functional training.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- an eight-week CrossFit training program
- What this could lead to
- If the program changes immune markers, it could support exercise as a low-cost way to improve immune health in people who are sedentary.
- What could go wrong
- The study is small, with 30 participants, and only measures immune cell counts, not whether people get sick less often. Results may not apply to women, older adults, or people with different fitness levels.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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30 people
The number who actually took part.
- Started
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May 2026
- Finished
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Jun 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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19 to 24 years
- Sex
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Male participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria:- Male participants aged 18 to 23 years * Currently enrolled as a student at Yalova University * Not regularly participating in exercise or sports training * Medically eligible to participate in CrossFit training * Willing and able to complete the eight-week CrossFit training program conducted three days per week * Willing to provide venous blood samples at the specified assessment times * Willing to provide written informed consent Exclusion Criteria:- Regular participation in exercise or sports training * History of a neurological disorder within the previous year * History of an auditory, visual, or vestibular disorder within the previous year * Serious upper- or lower-extremity injury within the previous six months * Presence of a medical condition that could prevent safe participation in the exercise program * Inability to complete the training or blood-sampling procedures * Withdrawal of voluntary consent
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Exercise Physiology Laboratory, Faculty of Sport Sciences, Karabuk University
Karabük, Karabük Province, Turkey (Türkiye)