New device aims to seal artery punctures faster and safer
NCT ID NCT03756558
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested a device called Cross-Seal that helps close large holes in the main leg artery after heart procedures. It involved 147 adults who needed artery access with large sheaths. The goal was to see if the device could stop bleeding quickly and safely without major complications.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Cross-Seal System (a suture-mediated vascular closure device)
What this could lead to
If successful, this device could provide a faster, safer way to close large artery punctures after heart procedures, reducing complications and recovery time.
What could go wrong
This is a single-arm study with no comparison group, and the device may still cause bleeding, infection, or other complications. Results may not apply to all patients or settings.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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Cardiothoracic and Vascular Surgeons
Austin, Texas, 78756, United States
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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Good Samaritan Hospital
Cincinnati, Ohio, 45220, United States
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Holston Valley Medical Center
Kingsport, Tennessee, 37660, United States
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INTEGRIS Cardiovascular Physicians
Oklahoma City, Oklahoma, 73112, United States
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Lankenau Institute for Medical Research
Wynnewood, Pennsylvania, 19096, United States
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Mt Sinai Medical Center
New York, New York, 10029, United States
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North Central Heart
Sioux Falls, South Dakota, 57108, United States
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River City Clinical Research
Jacksonville, Florida, 32207, United States
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Rutgers, The State University of New Jersey
Piscataway, New Jersey, 08854, United States
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Sentara Medical Group
Norfolk, Virginia, 23502, United States
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St. David's Heart and Vascular dba Austin heart
Austin, Texas, 78756, United States
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Swedish Medical Center
Seattle, Washington, 98122, United States
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Texas Heart Institute and Baylor St. Luke's Medical Center
Houston, Texas, 77030, United States
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The Trustees of Columbia University in the City of New York
New York, New York, 10032, United States
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University of Iowa Hospital
Iowa City, Iowa, 52242, United States
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University of Rochester
Rochester, New York, 14642, United States
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University of South Florida
Tampa, Florida, 33620, United States
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Vascular Institute of the Rockies
Denver, Colorado, 80218, United States