New hope for sickle cell patients suffering from debilitating erections

NCT ID NCT03938454

Summary

This study tested whether a drug called crizanlizumab could reduce the frequency of painful, prolonged erections (priapism) in men with sickle cell disease. 36 male participants aged 12 and older, who experienced frequent priapism episodes, received the drug by IV infusion for one year. Researchers measured how much the drug reduced these events and monitored for side effects.

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Contacts and locations

Locations

  • Brody School of Medicine

    Greenville, North Carolina, 27834, United States

  • Childrens Hosp Boston Dept of Hematology

    Boston, Massachusetts, 02115, United States

  • Childrens National Hospital

    Washington D.C., District of Columbia, 20010, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • Emory University School of Medicine

    Atlanta, Georgia, 30303, United States

  • Foundation for Sickle Cell Disease Research

    Hollywood, Florida, 33021, United States

  • LSU Medical Center

    Shreveport, Louisiana, 71130, United States

  • Montefiore Medical Center

    The Bronx, New York, 10461, United States

  • Prisma Health Upstate

    Greenville, South Carolina, 29615, United States

  • University Of Alabama

    Birmingham, Alabama, 35294, United States

  • University of Connecticut Health Center

    Farmington, Connecticut, 06030, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15213-2548, United States

  • University of Texas Medical School

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.