New drug shows promise in leukemia battle

NCT ID NCT03258931

First seen Apr 10, 2026 · Last updated Apr 26, 2026 · Updated 2 times

Summary

This study tested a new drug, crenolanib, against an existing drug, midostaurin, in adults aged 18-60 with a specific genetic type of acute myeloid leukemia (FLT3-mutated AML). Participants received one of the two drugs alongside standard chemotherapy and, if eligible, a bone marrow transplant. The goal was to see which drug better prevents the cancer from returning and improves survival.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Beth Israel Deacnss Medical Center Oncology

    Boston, Massachusetts, 02215, United States

  • City of Hope National Medical Center

    Duarte, California, 91010, United States

  • Columbia University

    New York, New York, 10032, United States

  • Cornell University

    New York, New York, 10065, United States

  • Dana-Farber Cancer Insitute

    Boston, Massachusetts, 02215, United States

  • Henry Ford Health System

    Detroit, Michigan, 48202, United States

  • Indiana University

    Indianapolis, Indiana, 46206-5149, United States

  • John Theurer Cancer Center at Hackensack UMC

    Hackensack, New Jersey, 07601, United States

  • Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Memorial Sloan-Kettering Cancer Center

    New York, New York, 10065, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

  • Mount Sinai

    New York, New York, 10029-6574, United States

  • New York University

    New York, New York, 10016, United States

  • Oregon Health and Science University

    Portland, Oregon, 97239, United States

  • Ronald Reagan UCLA Medical Center

    Los Angeles, California, 90095, United States

  • Roswell Park

    Buffalo, New York, 14263, United States

  • Rush Medical Center

    Chicago, Illinois, 60612, United States

  • Rutgers Cancer Institute of New Jersey

    New Brunswick, New Jersey, 08901, United States

  • The UNC Lineberger Comprehensive Cancer Center

    Chapel Hill, North Carolina, 27514, United States

  • US Davis Health

    Sacramento, California, 95817, United States

  • University of Chicago

    Chicago, Illinois, 60637, United States

  • University of Illinois at Chicago

    Chicago, Illinois, 60612, United States

  • University of Iowa Hospitals and Clinics

    Iowa City, Iowa, 52242, United States

  • University of Kansas

    Kansas City, Kansas, 66160, United States

  • University of Minnesota

    Minneapolis, Minnesota, 55455, United States

  • University of Rochester Medical Center

    New York, New York, 14642, United States

  • University of Virginia Health System

    Charlottesville, Virginia, 22908, United States

  • Wake Forest Baptist Health, Section on Hematology & Oncology

    Winston-Salem, North Carolina, 27157, United States

  • Yale Cancer Center

    New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.