Can vitamin e cream soothe chemo's painful hand-foot side effect?

NCT ID NCT05939726

First seen Jan 17, 2026 · Last updated Apr 29, 2026 · Updated 17 times

Summary

This study tested whether moisturizing creams, with or without vitamin E from palm oil, can help resolve hand-foot skin reactions caused by the chemotherapy drug capecitabine. 145 cancer patients with mild (grade 1) hand-foot skin reaction took part. The goal was to see if adding these creams to standard urea-based cream improves skin healing.

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Contacts and locations

Locations

  • Sarawak General Hospital

    Kuching, Sarawak, 93586, Malaysia

Conditions

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