New combo therapy aims to stop deadly meningitis before it starts
NCT ID NCT03945448
First seen May 05, 2026 · Last updated May 05, 2026
Summary
This study tests whether giving a single, stronger dose of antifungal medicine (liposomal amphotericin) along with standard fluconazole can prevent cryptococcal meningitis in HIV-positive adults who have the fungus in their blood but no symptoms. About 356 participants in Uganda will be randomly assigned to the enhanced treatment or standard care alone. The goal is to see if the stronger treatment reduces the number of people who develop meningitis over 24 weeks.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CRYPTOCOCCAL MENINGITIS are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
infectious Disease Institute Kampala,Uganda
RECRUITINGKampala, Uganda
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.