New drug cocktail aims to wipe out rectal cancer before surgery
NCT ID NCT05358704
First seen Jan 06, 2026 · Last updated Apr 29, 2026 · Updated 19 times
Summary
This study tests whether giving a powerful mix of chemotherapy drugs (FOLFOXIRI) along with standard chemoradiation before surgery can make rectal cancer disappear completely. About 38 adults with rectal cancer will receive the experimental treatment, then have scans to check tumor response. The goal is to see if this approach is safe and effective at achieving a complete response before surgery.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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RWJBarnabas Health - Community Medical Center
Toms River, New Jersey, 08755, United States
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RWJBarnabas Health - Monmouth Medical Center
Lakewood, New Jersey, 08701, United States
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RWJBarnabas Health - Robert Wood Johnson University Hospital, Somerset
Somerset, New Jersey, 08873, United States
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RWJBarnabas Health - Saint Barnabas Medical Center, Livingston
Livingston, New Jersey, 07039, United States
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Rutgers, The State University of New Jersey
New Brunswick, New Jersey, 08901, United States
Conditions
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