New drug aims to quiet chronic cough in lung disease patients
NCT ID NCT06360094
First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 34 times
Summary
This study tested an experimental drug called BI 1839100 to see if it could reduce chronic coughing in adults with idiopathic pulmonary fibrosis (IPF) or progressive pulmonary fibrosis (PPF). Participants took different doses of the drug or a placebo for 12 weeks. Coughing was measured using a portable device and questionnaires, and lung function was also checked. The study aimed to find the best dose to ease coughing and improve quality of life.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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A & A Research Consultants, LLC
Edinburg, Texas, 78539, United States
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Advanced Pulmonary Research
Warren, Michigan, 48088, United States
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Affiliated Hospital, Xuzhou Medical college
Xuzhou, 221009, China
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Akershus Universitetssykehus HF
Lørenskog, 1478, Norway
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Amphia Ziekenhuis
Breda, 4818 CK, Netherlands
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Anhui Provincial Hospital
Hefei, 230001, China
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Asan Medical Center
Seoul, 05505, South Korea
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Azienda Ospedaliera Universitaria di Padova
Padova, 35128, Italy
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CHR de la Citadelle
Liège, 4000, Belgium
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CIMS Studienzentrum Bamberg GmbH
Bamberg, 96049, Germany
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CTC Clinical Trial Consultants AB
Uppsala, 752 37, Sweden
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Centre Hospitalier de l'Universite de Montreal (CHUM)
Montreal, Quebec, H2X 3E4, Canada
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China Shenyang Chest Hospital
Shenyang, 110000, China
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Christchurch Hospital
Christchurch, 8011, New Zealand
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Chulalongkorn Hospital
Bangkok, 10330, Thailand
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Clinical Research Associates of Central PA
DuBois, Pennsylvania, 15801, United States
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Clinical Research Specialists LLC - Kissimmee
Kissimmee, Florida, 34746, United States
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Coastal Carolina Health Care, P.A. Pulmonary and Sleep Medicine
New Bern, North Carolina, 28562, United States
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Columbia University Medical Center-New York Presbyterian Hospital
New York, New York, 10032, United States
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Critical Care, Pulmonary and Sleep Associates
Lakewood, Colorado, 80228, United States
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Duke University Medical Center
Durham, North Carolina, 27710, United States
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Erasmus Medisch Centrum-ROTTERDAM-50697
Rotterdam, 3015 GD, Netherlands
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First Affiliated Hospital of Guangzhou Medical University
Guangzhou, 510120, China
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Fondazione Policlinico Universitario A. Gemelli IRCCS
Roma, 00168, Italy
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Gordon & Leslie Diamond Health Care Centre (UBC)
Vancouver, British Columbia, V5Z 1M9, Canada
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Greenlane Clinical Centre
One Tree Hill, Auckland, 1051, New Zealand
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HOP Avicenne
Bobigny, 93000, France
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HOP Bretonneau
Tours, 37000, France
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HOP CHU Caen
Caen, 14033, France
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HOP Michallon
La Tronche, 38700, France
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HOP Nord Laennec
Nantes, 44093, France
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HOP d'Angers
Angers, 49933, France
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HYKS Keuhkosairauksien tutkimusyksikkö
Helsinki, 00029, Finland
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Haukeland Universitetssykehus
Bergen, N-5021, Norway
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Hospital Central de Asturias
Oviedo, 33011, Spain
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Hospital Quirónsalud Madrid
Pozuelo de Alarcón, 28223, Spain
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Hospital Sultan Idris Shah Serdang
Kajang, 43000, Malaysia
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Hospital Universitari Vall D Hebron
Barcelona, 08035, Spain
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Hospital Universitario Virgen de la Victoria
Málaga, 29010, Spain
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Hospital de Galdakao
Galdakao, 48960, Spain
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Hospital of Heraklion (PAGNI)
Crete, 71500, Greece
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Icahn School of Medicine at Mount Sinai
New York, New York, 10029, United States
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Inje University Sanggye Paik Hospital
Seoul, 01757, South Korea
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Institut Perubatan Respiratori
Kuala Lumpur, 53000, Malaysia
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Kanagawa Cardiovascular and Respiratory Center
Kanagawa, Yokohama, 236-0051, Japan
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Kaohsiung Medical University Chung-Ho Memorial Hospital
Kaohsiung City, 807, Taiwan
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Krankenhaus Bethanien gGmbH
Solingen, 42699, Germany
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Kyushu University Hospital
Fukuoka, Fukuoka, 812-8582, Japan
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Launceston Respiratory & Sleep Centre
Launceston, Tasmania, 7250, Australia
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Lowcountry Lung and Critical Care
Charleston, South Carolina, 29406, United States
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Lung Research Victoria
Footscray, Victoria, 3011, Australia
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Medizinische Hochschule Hannover
Hanover, 30625, Germany
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Memorial Hospital Gulfport
Gulfport, Mississippi, 39501, United States
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Nanjing Drum Tower Hospital
Nanjing, 210008, China
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National Center for Global Health and Medicine
Tokyo, Shinjuku-ku, 162-8655, Japan
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National Hospital Organization Himeji Medical Center
Hyogo, Himeji, 670-8520, Japan
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National Hospital Organization Kyushu Medical Center
Fukuoka, Fukuoka, 810-8563, Japan
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Northern Westchester Hospital
Mount Kisco, New York, 10549, United States
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Odense University Hospital
Odense, 5000, Denmark
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Oslo Universitetssykehus HF, Rikshospitalet
Oslo, N-0372, Norway
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Ospedale Classificato San Giuseppe
Milan, 20123, Italy
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Oulun yliopistollinen keskussairaala
Oulu, 90220, Finland
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People's Hospital of Sichuan Province
Chengdu, 610072, China
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Pol. Universitario Tor Vergata
Roma, 00133, Italy
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Pulmonary Associates of Richmond, Inc.
Richmond, Virginia, 23230, United States
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Ramathibodi Hospital
Ratchatewi, 10400, Thailand
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Royal Brompton Hospital
London, SW3 6NP, United Kingdom
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Royal Devon and Exeter Hospital, Wonford
Exeter, EX2 5DW, United Kingdom
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Royal Lancaster Infirmary
Lancaster, LA1 4RP, United Kingdom
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Ruhrlandklinik, Westdeutsches Lungenzentrum am Universitätsklinikum Essen gGmbH
Essen, 45239, Germany
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Sapporo Medical University Hospital
Hokkaido, Sapporo, 060-8543, Japan
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Shanghai Pulmonary Hospital
Shanghai, 200433, China
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Singapore General Hospital
Singapore, 169608, Singapore
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Skånes universitetssjukhus, Lund
Lund, 221 85, Sweden
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Songklanagarind Hospital
Songkhla, 90110, Thailand
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Southampton General Hospital
Southampton, SO16 6YD, United Kingdom
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Southeastern Research Center-Winston Salem-69289
Winston-Salem, North Carolina, 27103, United States
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Spartanburg Medical Research
Spartanburg, South Carolina, 29303, United States
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Srinagarind Hospital
Khon Kaen, 40002, Thailand
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St. Joseph's Healthcare Hamilton
Hamilton, Ontario, L8N 4A6, Canada
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TYKS
Turku, 20520, Finland
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Taichung Veterans General Hospital
Taichung, 40705, Taiwan
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Temple University Hospital
Philadelphia, Pennsylvania, 19140, United States
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The Iowa Clinic, PC
West Des Moines, Iowa, 50266, United States
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The Second Xiangya Hospital Of Central South University
Changsha, 410011, China
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Thoraxklinik-Heidelberg gGmbH am Universitätsklinikum Heidelberg
Heidelberg, 69126, Germany
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Tianjin Medical University General Hospital
Tianjin, 30052, China
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Toho University Omori Medical Center
Tokyo, Ota-ku, 143-8541, Japan
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Tokushima University Hospital
Tokushima, Tokushima, 770-8503, Japan
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Univ. Gen. Hosp. of Patras
Pátrai, 26504, Greece
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University Thomayer´s Hospital
Prague, 140 59, Czechia
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University of Alabama at Birmingham
Birmingham, Alabama, 35294, United States
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University of Fukui Hospital
Fukui, Yoshida-gun, 910-1193, Japan
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Universitätsklinikum Aachen, AöR
Aachen, 52074, Germany
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Universitätsklinikum Freiburg
Freiburg im Breisgau, 79106, Germany
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Waikato Hospital
Hamilton, 3240, New Zealand
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West China Hospital of Sichuan University
Chengdu, 610041, China
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Wythenshawe Hospital
Manchester, M23 9LT, United Kingdom
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Zhejiang Hospital
Hangzhou, 310013, China
Conditions
Explore the condition pages connected to this study.