Drug trial aims to quiet debilitating cough in scarred lungs

NCT ID NCT06360094

Terminated Symptom relief Sponsor: Boehringer Ingelheim Source: ClinicalTrials.gov ↗

Summary

This study tested an oral medicine called BI 1839100 to see if it could reduce chronic cough in adults with idiopathic pulmonary fibrosis (IPF) or progressive pulmonary fibrosis (PPF). About 85 participants were randomly assigned to receive either the study drug at different doses or a placebo for 12 weeks. Researchers measured cough frequency and severity using wearable devices and questionnaires to compare results between the groups. The trial was terminated early.

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Contacts and locations

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Locations

A & A Research Consultants, LLC

Edinburg, Texas, 78539, United States
Advanced Pulmonary Research

Warren, Michigan, 48088, United States
Affiliated Hospital, Xuzhou Medical college

Xuzhou, 221009, China
Akershus Universitetssykehus HF

Lørenskog, 1478, Norway
Amphia Ziekenhuis

Breda, 4818 CK, Netherlands
Anhui Provincial Hospital

Hefei, 230001, China
Asan Medical Center

Seoul, 05505, South Korea
Azienda Ospedaliera Universitaria di Padova

Padua, 35128, Italy
CHR de la Citadelle

Liège, 4000, Belgium
CIMS Studienzentrum Bamberg GmbH

Bamberg, 96049, Germany
CTC Clinical Trial Consultants AB

Uppsala, 752 37, Sweden
Centre Hospitalier de l'Universite de Montreal (CHUM)

Montreal, Quebec, H2X 3E4, Canada
China Shenyang Chest Hospital

Shenyang, 110000, China
Christchurch Hospital

Christchurch, 8011, New Zealand
Chulalongkorn Hospital

Bangkok, 10330, Thailand
Clinical Research Associates of Central PA

DuBois, Pennsylvania, 15801, United States
Clinical Research Specialists LLC - Kissimmee

Kissimmee, Florida, 34746, United States
Coastal Carolina Health Care, P.A. Pulmonary and Sleep Medicine

New Bern, North Carolina, 28562, United States
Columbia University Medical Center-New York Presbyterian Hospital

New York, New York, 10032, United States
Critical Care, Pulmonary and Sleep Associates

Lakewood, Colorado, 80228, United States
Duke University Medical Center

Durham, North Carolina, 27710, United States
Erasmus Medisch Centrum-ROTTERDAM-50697

Rotterdam, 3015 GD, Netherlands
First Affiliated Hospital of Guangzhou Medical University

Guangzhou, 510120, China
Fondazione Policlinico Universitario A. Gemelli IRCCS

Roma, 00168, Italy
Gordon & Leslie Diamond Health Care Centre (UBC)

Vancouver, British Columbia, V5Z 1M9, Canada
Greenlane Clinical Centre

One Tree Hill, Auckland, 1051, New Zealand
HOP Avicenne

Bobigny, 93000, France
HOP Bretonneau

Tours, 37000, France
HOP CHU Caen

Caen, 14033, France
HOP Michallon

La Tronche, 38700, France
HOP Nord Laennec

Nantes, 44093, France
HOP d'Angers

Angers, 49933, France
HYKS Keuhkosairauksien tutkimusyksikkö

Helsinki, 00029, Finland
Haukeland Universitetssykehus

Bergen, N-5021, Norway
Hospital Central de Asturias

Oviedo, 33011, Spain
Hospital Quirónsalud Madrid

Pozuelo de Alarcón, 28223, Spain
Hospital Sultan Idris Shah Serdang

Kajang, 43000, Malaysia
Hospital Universitari Vall D Hebron

Barcelona, 08035, Spain
Hospital Universitario Virgen de la Victoria

Málaga, 29010, Spain
Hospital de Galdakao

Galdakao, 48960, Spain
Hospital of Heraklion (PAGNI)

Crete, 71500, Greece
Icahn School of Medicine at Mount Sinai

New York, New York, 10029, United States
Inje University Sanggye Paik Hospital

Seoul, 01757, South Korea
Institut Perubatan Respiratori

Kuala Lumpur, 53000, Malaysia
Kanagawa Cardiovascular and Respiratory Center

Kanagawa, Yokohama, 236-0051, Japan
Kaohsiung Medical University Chung-Ho Memorial Hospital

Kaohsiung City, 807, Taiwan
Krankenhaus Bethanien gGmbH

Solingen, 42699, Germany
Kyushu University Hospital

Fukuoka, Fukuoka, 812-8582, Japan
Launceston Respiratory & Sleep Centre

Launceston, Tasmania, 7250, Australia
Lowcountry Lung and Critical Care

Charleston, South Carolina, 29406, United States
Lung Research Victoria

Footscray, Victoria, 3011, Australia
Medizinische Hochschule Hannover

Hanover, 30625, Germany
Memorial Hospital Gulfport

Gulfport, Mississippi, 39501, United States
Nanjing Drum Tower Hospital

Nanjing, 210008, China
National Center for Global Health and Medicine

Tokyo, Shinjuku-ku, 162-8655, Japan
National Hospital Organization Himeji Medical Center

Hyogo, Himeji, 670-8520, Japan
National Hospital Organization Kyushu Medical Center

Fukuoka, Fukuoka, 810-8563, Japan
Northern Westchester Hospital

Mount Kisco, New York, 10549, United States
Odense University Hospital

Odense, 5000, Denmark
Oslo Universitetssykehus HF, Rikshospitalet

Oslo, N-0372, Norway
Ospedale Classificato San Giuseppe

Milan, 20123, Italy
Oulun yliopistollinen keskussairaala

Oulu, 90220, Finland
People's Hospital of Sichuan Province

Chengdu, 610072, China
Pol. Universitario Tor Vergata

Roma, 00133, Italy
Pulmonary Associates of Richmond, Inc.

Richmond, Virginia, 23230, United States
Ramathibodi Hospital

Ratchatewi, 10400, Thailand
Royal Brompton Hospital

London, SW3 6NP, United Kingdom
Royal Devon and Exeter Hospital, Wonford

Exeter, EX2 5DW, United Kingdom
Royal Lancaster Infirmary

Lancaster, LA1 4RP, United Kingdom
Ruhrlandklinik, Westdeutsches Lungenzentrum am Universitätsklinikum Essen gGmbH

Essen, 45239, Germany
Sapporo Medical University Hospital

Hokkaido, Sapporo, 060-8543, Japan
Shanghai Pulmonary Hospital

Shanghai, 200433, China
Singapore General Hospital

Singapore, 169608, Singapore
Skånes universitetssjukhus, Lund

Lund, 221 85, Sweden
Songklanagarind Hospital

Songkhla, 90110, Thailand
Southampton General Hospital

Southampton, SO16 6YD, United Kingdom
Southeastern Research Center-Winston Salem-69289

Winston-Salem, North Carolina, 27103, United States
Spartanburg Medical Research

Spartanburg, South Carolina, 29303, United States
Srinagarind Hospital

Khon Kaen, 40002, Thailand
St. Joseph's Healthcare Hamilton

Hamilton, Ontario, L8N 4A6, Canada
TYKS

Turku, 20520, Finland
Taichung Veterans General Hospital

Taichung, 40705, Taiwan
Temple University Hospital

Philadelphia, Pennsylvania, 19140, United States
The Iowa Clinic, PC

West Des Moines, Iowa, 50266, United States
The Second Xiangya Hospital Of Central South University

Changsha, 410011, China
Thoraxklinik-Heidelberg gGmbH am Universitätsklinikum Heidelberg

Heidelberg, 69126, Germany
Tianjin Medical University General Hospital

Tianjin, 30052, China
Toho University Omori Medical Center

Tokyo, Ota-ku, 143-8541, Japan
Tokushima University Hospital

Tokushima, Tokushima, 770-8503, Japan
Univ. Gen. Hosp. of Patras

Pátrai, 26504, Greece
University Thomayer´s Hospital

Prague, 140 59, Czechia
University of Alabama at Birmingham

Birmingham, Alabama, 35294, United States
University of Fukui Hospital

Fukui, Yoshida-gun, 910-1193, Japan
Universitätsklinikum Aachen, AöR

Aachen, 52074, Germany
Universitätsklinikum Freiburg

Freiburg im Breisgau, 79106, Germany
Waikato Hospital

Hamilton, 3240, New Zealand
West China Hospital of Sichuan University

Chengdu, 610041, China
Wythenshawe Hospital

Manchester, M23 9LT, United Kingdom
Zhejiang Hospital

Hangzhou, 310013, China

Conditions

Explore the condition pages connected to this study.

IDIOPATHIC PULMONARY FIBROSIS PROGRESSIVE PULMONARY FIBROSIS