Lifeline for sickle cell patients: drug access extended in new study

NCT ID NCT04657822

Recruiting now Disease control Sponsor: Novartis Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 22 times

Summary

This study offers ongoing access to crizanlizumab for people with sickle cell disease who have already completed a Novartis-sponsored trial and are benefiting from the drug. About 130 participants will continue receiving treatment to manage their condition. The goal is to provide uninterrupted care until the drug becomes commercially available or reimbursed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-••••

Locations

Augusta University Georgia
RECRUITING

Augusta, Georgia, 30912, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
Childrens Hospital of Philadelphia
ACTIVE_NOT_RECRUITING

Philadelphia, Pennsylvania, 19104-4399, United States
Childrens National Hospital
ACTIVE_NOT_RECRUITING

Washington D.C., District of Columbia, 20010, United States
Cook Childrens Medical Center
COMPLETED

Fort Worth, Texas, 76104, United States
East Carolina University
COMPLETED

Greenville, North Carolina, 27834, United States
East Carolina University
COMPLETED

Greenville, North Carolina, 27858, United States
Novartis Investigative Site
COMPLETED

Brussels, 1000, Belgium
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Laken, 1020, Belgium
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Liège, 4000, Belgium
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Salvador, Estado de Bahia, 41253-190, Brazil
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Ribeirão Preto, São Paulo, 14051-140, Brazil
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

São Paulo, São Paulo, 01232-010, Brazil
Novartis Investigative Site
RECRUITING

Valledupar, Cesar Department, 200001, Colombia
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Cali, Valle del Cauca Department, 760032, Colombia
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Montería, 230004, Colombia
Novartis Investigative Site
COMPLETED

Créteil, 94010, France
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Paris, 75015, France
Novartis Investigative Site
COMPLETED

Paris, 75015, France
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Heidelberg, 69120, Germany
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Padova, PD, 35128, Italy
Novartis Investigative Site
COMPLETED

Orbassano, TO, 10043, Italy
Novartis Investigative Site
RECRUITING

Beirut, 113-0236, Lebanon
Novartis Investigative Site
RECRUITING

Tripoli, 1434, Lebanon
Novartis Investigative Site
RECRUITING

Khoudh, 123, Oman
Novartis Investigative Site
COMPLETED

Barcelona, 08035, Spain
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Madrid, 28009, Spain
Novartis Investigative Site
WITHDRAWN

Hatay, Antakya, 31101, Turkey (Türkiye)
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Adana, Saricam, 01330, Turkey (Türkiye)
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Adana, Yuregir, 01250, Turkey (Türkiye)
University Of Alabama
RECRUITING

Birmingham, Alabama, 35233, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

SICKLE CELL DISEASE