Does adding epinephrine improve spider vein treatment?

NCT ID NCT07342413

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding epinephrine to a glycerin and lidocaine mixture improves the treatment of small leg veins (telangiectasias). Twenty adults will have one leg treated with the standard mixture and the other with the mixture plus epinephrine. Doctors will rate vein clearance, and patients will report pain and satisfaction.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
glycerin with lidocaine and epinephrine
What this could lead to
If successful, this could show that adding epinephrine improves vein clearance or reduces pain during sclerotherapy.
What could go wrong
This is a very small, early-phase study with only 20 participants, so results may not apply to everyone. The treatment is for cosmetic improvement, not a cure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • West Dermatology Research Center

    San Diego, California, 92121, United States