Does adding epinephrine improve spider vein treatment?

NCT ID NCT07342413

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding epinephrine to a glycerin and lidocaine mixture improves the treatment of small leg veins (telangiectasias). Twenty adults will have one leg treated with the standard mixture and the other with the mixture plus epinephrine. Doctors will rate vein clearance, and patients will report pain and satisfaction.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

glycerin with lidocaine and epinephrine

What this could lead to

If successful, this could show that adding epinephrine improves vein clearance or reduces pain during sclerotherapy.

What could go wrong

This is a very small, early-phase study with only 20 participants, so results may not apply to everyone. The treatment is for cosmetic improvement, not a cure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

telangiectasis varicose disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • West Dermatology Research Center

    San Diego, California, 92121, United States