New study aims to make dental extractions Pain-Free by testing better anesthetics

NCT ID NCT07597408

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two local anesthetics (articaine and buffered lidocaine) for extracting upper teeth. The goal is to see if one can numb the tooth effectively without needing a separate, painful injection into the palate. Fifty healthy adults needing extraction of a matching pair of upper teeth will receive each anesthetic in separate sessions, and researchers will measure pain, numbness onset, and duration.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

articaine hydrochloride and buffered lidocaine hydrochloride

What this could lead to

If one anesthetic works better, it could make dental extractions less painful and reduce patient fear by avoiding a separate injection into the palate.

What could go wrong

This is a small, early study (50 people) comparing two well-known drugs, so the results may not apply to everyone or change practice dramatically.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Latakia university

    Latakia, Syria