New bone drug copycat put to the test in healthy volunteers

NCT ID NCT05245669

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial compared a new biosimilar version of the bone drug denosumab (called ENZ215) with the already-approved brand-name drug Prolia. 207 healthy adult men received a single shot of either the new drug or Prolia. The goal was simply to see if the new version behaves the same way in the body—not to treat any disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

denosumab (a bone-strengthening drug)

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • MC Comac Medical

    Sofia, Sofia City Province, 1000, Bulgaria

  • MTZ Clinical Research powered by Pratia, Pratia S.A

    Warsaw, 02-172, Poland