New drug cocktail offers hope for Tough-to-Treat leukemia

NCT ID NCT04774393

First seen Nov 01, 2025 · Last updated Jun 12, 2026 · Updated 29 times

Summary

This study is for people with acute myeloid leukemia (AML) that has come back or not improved with standard treatments. It tests a combination of three drugs: a chemotherapy pill (ASTX727), a targeted therapy (venetoclax), and another targeted drug (ivosidenib or enasidenib) based on the patient's specific mutation. The goal is to see if this combination is safe and can help control the leukemia.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.