New drug combo shows promise for Hard-to-Treat cancers

NCT ID NCT00045201

First seen Oct 01, 2025 · Last updated May 07, 2026 · Updated 32 times

Summary

This early-phase trial tests the safety and best dose of combining two drugs, erlotinib and irinotecan, in 60 adults with advanced solid tumors that have not responded to standard treatments. The goal is to see if the combination can shrink tumors or slow their growth. Participants must have tumors that overexpress a protein called EGFR and be willing to provide blood and tissue samples.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ADULT SOLID NEOPLASM are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States

Conditions

Explore the condition pages connected to this study.